Contributions to the Research and Education  in Ophthalmology

Matthias J. Monhart

Through the past 20+ years I have transitioned from an electronics and software developer to an expert in structural and functional testing, leading hardware and software projects to success - e.g. the Haag-Streit Octopus© 900, the EyeSuite™ Software in general and more specifically the EyeSuite Perimetry software.

In my recent past I contributed significantly to the success of the ZEISS HFA3 and lead a research team to develop the next generation standard of care test program – the 24-2C which is available on the HFA3 and can be considered the new standard in Glaucoma testing.  I consulted students in their diploma projects and thesis utilizing VR technology in visual functional testing: a field with an enormous potential.

In all this I try to put technology in the service of patients and consider the simple yet meaningful visualization of information as key factor for success – something I deem valid for most all areas.

Publications and contributionsI

It was my pleasure to author in 2020 - together with Paul Artes - a review and outlook on perimetry: “Eine kurz(weilige) Geschichte der Perimetrie / Une histoire divertissante de la périmetrie” in the 25 year anniversary edition of the Swiss Ophta Journal of Ophthalmology.

PubMed.gov listed publications

• Brandão LM, Monhart M, Schötzau A, Ledolter AA, Palmowski-Wolfe AM., Applying a New Automated Perimetry Pattern Based on the Stimulus Distribution of the Multifocal ERG to Improve Structure-Function Investigation in Glaucoma., J Ophthalmol. 2017;2017:8780934.
• Brandao LM, Ledolter AA, Monhart M, Schötzau A, Palmowski-Wolfe AM., Ganglion cell layer segmentation and the two-flash multifocal electroretinogram improve structure function analysis in early glaucoma., Graefes Arch Clin Exp Ophthalmol. 2017 Oct;255(10):1991-2000.
• Brandao LM, Monhart M, Schötzau A, Ledolter AA, Palmowski-Wolfe AM., Wavelet decomposition analysis in the two-flash multifocal ERG in early glaucoma: a comparison to ganglion cell analysis and visual field., Doc Ophthalmol. 2017 Aug;135(1):29-42.
• Ledolter A., Monhart M., Schoetzau A., Todorova M., Palmowski-Wolfe A. (2015). Structural and functional changes in glaucoma: Comparing the two-flash multifocal electroretinogram to optical coherence tomography and visual fields. Documenta Ophthalmologica, 130 (3), 197–209.
• Luithardt AF, Meisner C, Monhart M, Krapp E, Mast A, Schiefer U., Validation of a new static perimetric thresholding strategy (GATE)., Br J Ophthalmol. 2015 Jan;99(1):11-5.
• Monhart M. What are the options of psychophysical approaches in glaucoma? Surv Ophthalmol 2007;52:S127– S133.
• Brown SM, Bradley JC, Monhart MJ, et al. Normal values for Octopus tendency oriented perimetry in children 7 through 13 years old. Graefes Arch Clin Exp Ophthalmol. 2005;243: 886–893.

• Non-PubMed listed publications

• Monhart M. Artes P., Eine kurz(weilig)e Geschichte der Perimetrie / Une histoire divertissante de la périmétrie. Ophta Sonderausgabe 25 Jahre, September 2020
• Buerki E, Monhart M. An update to Octopus perimetry. Eur Ophthal Rev 2007;12:20-2.
• Buerki E, Monhart M. Update Octopus Perimetrie 2: Bildung von Messpunkt Clustern. Optha. 2007;2:9-13.
• Monhart M, Zulauf M. Conversion of the Octopus visual-field index LV to the Zeiss- Humphrey field analyzer index PSD for the glaucoma risk calculator S.T.A.R. Ophta. 2006;1:15-16.

• WGC / World Glaucoma Congress

• Matthias Monhart, Gary Lee, Aiko Iwase, John Flanagan: Selecting additional test locations to enhance the 24-2 pattern using a scoring system, 7^th World Glaucoma Congress 2017, P-WT-309

• ARVO/IOVS/TVST Presentations

• Gary C Lee, Matthias Monhart, Thomas Callan, Buck Cunningham, Sophia Yu, Mary K Durbin, Boel Bengtsson, Aiko Iwase, John G Flanagan, Anders Heijl; Performance of a modified 24-2 test pattern using SITA Faster. Invest. Ophthalmol. Vis. Sci. 2018;59(9):6032.
• Luke Xiang-Yu Chong, Paul H Artes, Michael Wall, Thomas Callan, Vincent Michael Patella, Gary C Lee, Matthias Monhart, John G Flanagan; Perimetric Threshold Predictability Between Goldmann Size III and V Stimuli. Invest. Ophthalmol. Vis. Sci. 2017;58(8):2842.
• Livia Brandao, Matthias Monhart, Andreas Schötzau, Anna Ledolter, Anja M Palmowski-Wolfe; Structure function analysis in early glaucoma: Improved sensitivity of the mf103 compared to the G2 test pattern. Invest. Ophthalmol. Vis. Sci. 2016;57(12):385.
• John G Flanagan, Paul H. Artes, Michael Wall, Esther Young, Thomas Callan, Vincent Michael Patella, Matthias Monhart, Gary C Lee; The Influence of Perimetric Stimulus Size on Defect Detectability in Early Glaucoma. Invest. Ophthalmol. Vis. Sci. 2016;57(12):
• Livia Mello Brandao, Matthias Monhart, Andreas Schötzau, Anna Ledolter, Anja M Palmowski-Wolfe; Structure-function investigation in Glaucoma: a new Automated Perimetry protocol. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):629.
• Livia Mello Brandao, Anna A Ledolter, Matthias Monhart, Andreas Schötzau, Anja M Palmowski-Wolfe; Increasing structure function correlation in glaucoma patients through segmentation of the macular ganglion cell layer. Invest. Ophthalmol. Vis. Sci. 2014;55(13):975.
• Margarita G. Todorova, Anja M. Palmowski-Wolfe, Hans Bebie, Josef Flammer, Matthias Monhart; A Comparison Between The Pulsed Ramp And The Normal Staircase Strategy Using The G Test Pattern. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5519.
• M. Monhart, F. Dannheim; Evaluation of a Non-Linear Trend Analysis. Invest. Ophthalmol. Vis. Sci. 2010;51(13):5499.
• M. Monhart, H. Bebie, E. Buerki; Receiver Operating Characteristics of a Novel Method of Visual Field Trend Analysis. Invest. Ophthalmol. Vis. Sci.2008;49(13):1154.
• M. Monhart, E. Buerki, H. Bebie, A. Palmowski–Wolfe; Calculation of the Abnormal Response Area as an Indicator of Visual Field Changes . Invest. Ophthalmol. Vis. Sci. 2006;47(13):3982.
• C.D. Brocard, A. Kawasaki, M. Monhart; The Influence of Vector Quality Assessment in Defining a Scotoma . Invest. Ophthalmol. Vis. Sci. 2006;47(13):795.
• A.M. Palmowski–Wolfe, M. Todorova, H. Bebie, M. Monhart; A Comparison Between a Pulsed Ramp Strategy and a G1 Test Pattern Using Normal Strategy . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4318.

• Reviewer for ophthalmic scientific journals

• Exceptional Reviewer for IOVS: Investigative Ophthalmology & Visual Science March 2018, Vol.59, 1539-1546. doi:10.1167/iovs.18-24048
• Exceptional Reviewer for TVST: Translational Vision Science & Technology October 2017, Vol.6, r. doi:10.1167/tvst.6.5.r

• Public Lecturing / Education

• Lectures on Structure/Function, Progression analysis and Perimetry at various congresses, e.g. Japanese Glaucoma Society and the Glaucoma Meeting Basel, Switzerland as well as lectures and workshops in support of educational events, e.g. from Allergan, MSD, ZEISS and Haag-Streit.

• Acknowledgement / Contributions to publications

• Andrew Turpin, Paul H. Artes, Allison M. McKendrick; The Open Perimetry Interface: An enabling tool for clinical visual psychophysics. Journal of Vision 2012;12(11):22. doi: 10.1167/12.11.22.
• Kovalska MP, Bürki E, Schoetzau A, Orguel SF, Orguel S, Grieshaber MC. Clinical evaluation of a novel populationbased regression analysis for detecting glaucomatous visual field progression. Klin Monatsbl Augenheilkd. 2011;228: 311-7.
• Rigmor C. Baraas, David H. Foster, Kinjiro Amano, Sérgio M. C. Nascimento; Color Constancy of Red-Green Dichromats and Anomalous Trichromats. Invest. Ophthalmol. Vis. Sci. 2010;51(4):2286-2293. doi: 10.1167/iovs.09-4576.
• Participant / Faculty for “Progression of Glaucoma: The 8th Consensus Report of the World Glaucoma Association”